Research
Dr. Dai’s long-term research goal is to discover, understand and ultimately address the root cause underlying disease, and devise the innovative therapies.
Biography
Dr. Ning Dai has a long-standing interest in the biology of RNA binding proteins and their roles in diseases like aging and cancer. She is among the first to study the signaling of mTOR-IMPs/IGF2BPs. In the past 15 years, she has identified IMPs as direct mTOR substrates, demonstrated the mTOR-dependent phosphorylation of IMPs are essential for RNA life cycle control, and illustrated the metabolic function of IMP2 in T2D pathophysiology using human genetics and murine models. Her recent work extends to the role IMP2 as a m6A reader in stem cell biology.