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Psilocybin Therapy Trial Psilocybin Therapy Resources

Psilocybin Therapy Resources

Innovative Research for Mental Health

Read about the latest in psychedelic research and how patients are responding.

Dying Patients are Fighting for Access to Psychedelics

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Safety of Psychedelics for Older Adults Assessed in New Study

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Cancer Patients say Psilocybin Can Be Both Therapy and “A Beautiful Experience”

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How A Psychedelic Drug Helps Cancer Patients Overcome Anxiety

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Two Cancer Patients Battle to Make Psilocybin Accessible for Palliative Care

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Navigating the Psychedelic Frontier

Study participants from prior psilocybin trials talk about their experience.

Psilocybin study participant her experience at Harbor-UCLA Medical Center
Cancer patient overcomes anxiety about death with psychedelics
Can magic mushrooms help cancer patients?
“I feel like death doesn’t frighten me.” Psychedelics help a cancer patient overcome anxiety
How magic mushrooms are used for healing

Publication in Medical Journals

Numerous peer-reviewed journals have featured thousands of articles focusing on psilocybin clinical research. Findings from these studies indicate psilocybin can be safely administered within medical settings. The emerging research holds promise for the potential of psilocybin therapy in alleviating depression and anxiety among individuals confronting life-threatening illnesses.

  • Grob CS, Danforth AL, Chopra GS, Hagerty M, McKay CR, Halberstadt AL, Greer GR. Pilot study of psilocybin treatment for anxiety in patients with advanced-stage cancer. Arch Gen Psychiatry. 2011 Jan;68(1):71-8. doi: 10.1001/archgenpsychiatry.2010.116. 
  • Ross S, Bossis A, Guss J, Agin-Liebes G, Malone T, Cohen B, Mennenga SE, Belser A, Kalliontzi K, Babb J, Su Z, Corby P, Schmidt BL. Rapid and sustained symptom reduction following psilocybin treatment for anxiety and depression in patients with life-threatening cancer: a randomized controlled trial. J Psychopharmacol. 2016 Dec;30(12):1165-1180. doi: 10.1177/0269881116675512.
  • Griffiths RR, Johnson MW, Carducci MA, Umbricht A, Richards WA, Richards BD, Cosimano MP, Klinedinst MA. Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-blind trial. J Psychopharmacol. 2016 Dec;30(12):1181-1197. doi: 10.1177/0269881116675513.
  • Agin-Liebes, G. I., Malone, T., Yalch, M. M., Mennenga, S. E., Ponté, K. L., Guss, J., … & Ross, S. (2020). Long-term follow-up of psilocybin-assisted psychotherapy for psychiatric and existential distress in patients with life-threatening cancer. Journal of Psychopharmacology, 34(2), 155-166. https://doi.org/10.1177/0269881119897615
  • Swift, T. C., Belser, A. B., Agin-Liebes, G., Devenot, N., Terrana, S., Friedman, H. L., … & Ross, S. (2017). Cancer at the dinner table: experiences of psilocybin-assisted psychotherapy for the treatment of cancer-related distress. Journal of Humanistic Psychology, 57(5), 488-519. https://journals.sagepub.com/doi/pdf/10.1177/0022167817715966
  • Bossis, A. P. (2021). Psilocybin, spirituality, and palliative care: Research and implications. Alternative and Complementary Therapies, 27(1), 14-17. https://www.liebertpub.com/doi/10.1089/act.2020.29309.apb
  • Grob, C.S, Bossis, A.P. and Griffiths, R.R. Use of the classic hallucinogen psilocybin for treatment of existential distress associated with cancer: in B. Carr and J. Steel (Eds.), Psychological Aspects of Cancer. 2nd Edition, New York, Springer, 2022. https://link.springer.com/chapter/10.1007/978-3-030-85702-8_5

The Psilocybin Trial at The Lundquist Institute and its partner sites is conducted by nonprofit academic institutions and clinics providing palliative care. The trial has no financial ties with any pharmaceutical company. All study findings will be made open access after the completion of the study. We are supporting the study by raising funds from private donations and foundation grants. Join us in finding new ways to live well and die at peace. Your tax-deductible donations will directly support this research trial and pave the way for the next frontier in palliative care.

This study has full regulatory approval and has begun treating participants at multiple sites. Additional funding is needed to meet our goal of enrolling 100 participants.

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