Kathy E Sietsema, MD

Kathy E Sietsema, MD

Investigator, The Lundquist Institute
Professor of Clinical Medicine, David Geffen School of Medicine at UCLA
Chief, Division of Respiratory & Critical Care Physiology & Medicine; Harbor-UCLA Medical Center
Director, Fellowship Training Program, Pulmonary and Critical Care Medicine, Harbor-UCLA Medical Center


Exercise Physiology, Clinical Applications of Exercise Testing, and Cardiovascular Adaptations to Exercise

Research Description

Dr. Sietsema’s focus is in exercise physiology and the use of exercise testing for assessing functional capacity in clinical and research settings. Her work includes investigations into the nature and significance of functional impairment in a wide range of chronic disease states, including: chronic heart failure, congenital heart diseases, chronic kidney disease and pulmonary hypertension.


  • MD, 1979; Northwestern University Medical School, Chicago, IL

Recent and/or Significant Publications

Sietsema KE, Amato A, Adler SG, Brass EP. Exercise capacity as a predictor of survival among patients with end stage renal disease. Kidney Int. 2004 Feb;65(2):719-24.
Arena RA and Sietsema KE. Cardiopulmonary exercise testing in patients with heart and lung diseases: Invited Review. Circulation. 2011;123:668–680.
Yang-Ting S, Aboulhosn J, Sun XG, Child J, Sietsema KE. Effects of pulmonary vasodilator therapy on ventilatory efficiency in adults with Eisenmenger syndrome, Congenital Heart Disease 2011; 6:139-146.
Balady GJ (Chairman), Arena R, Sietsema K, Myers J, Coke L, Fletcher GF, Forman D, Franklin B, Guazzi M, Gulati M, Keteyian SJ, Lavie CJ, Macko R, Mancini D, Milani RV. Clinician’s Guide to Cardiopulmonary Exercise Testing in Adults: A Scientific Statement from the American Heart Association Exercise, Cardiac Rehabilitation, and Prevention Committee of the Council on Clinical Cardiology; Council on Epidemiology and Prevention; Council on Peripheral Vascular Disease; and Interdisciplinary Council on Quality of Care and Outcomes Research. Circulation. 2010 Jul 13;122(2):191-225.
Wasserman K, Cox TA and Sietsema KE. Ventilatory regulation of arterial H+ (pH) during exercise. Respir Physiol Neurobiol. 2014 Jan 1;190:142-8.