Eli Ipp, MD
Investigator, The Lundquist Institute
Professor of Medicine, David Geffen School of Medicine at UCLA
Head of the Section of Diabetes and Metabolism, Harbor-UCLA Medical Center
Physiology of hormone secretion; Diabetes
Research DescriptionDr. Ipp’s laboratory utilizes a multidisciplinary approach that includes clinical phenotyping, biochemical measurement of biomarkers, mathematical modeling, genetics, and health services research methods to study the pathogenesis of diabetes and its complications. His research is focused on the following areas:
(a) Diabetic complications, with an emphasis on diabetic retinopathy. The work on diabetic eye disease focuses on prevention of blindness. Firstly, by investigating new pathogenetic pathways that may lead to retinal disease. Secondly, by designing improved methods to improve practical implementation of periodic eye screening to prevent vision loss.
(b) The role of the pancreatic beta cell in the development and progression of diabetes. This research includes clinical studies of prediabetes and diabetes.
- MD, 1968, University of the Witwatersrand Medical School, Johannesburg, South Africa
Recent and/or Significant Publications
Lu Y, Serpas L, Genter P, Mehranbrod C, Campa D, Ipp E. Disparities in diabetic retinopathy screening rates within minority populations: differences between African American and Hispanic Patients. Diabetes Care. 2015 Dec 30. dc152198. [Epub ahead of print] PMID 26721811.
Lu Y, Serpas L, Genter P, Campa D, and E Ipp. Divergent Perceptions of Barriers to Diabetic Retinal Screening: Patients vs. Providers and Staff. Preventing Chronic Disease. 2016 Oct 6;13:E140. doi: 10.5888/pcd13.160193.
Kuo JZ, Guo X, Klein R, Klein BE, Genter P, Roll K, Hai Y, Goodarzi MO, Rotter JI, Chen YD, Ipp E. Adiponectin, insulin sensitivity and diabetic retinopathy in Latinos with type 2 diabetes. J Clin Endocrinol Metab. 2015; 100(9):3348-3355.
Kuo JZ, Guo X, Klein R, Klein BE, Weinreb RN, Genter P, Hsiao FC, Goodarzi MO, Rotter JI, Chen YD, Ipp E. Association of fasting insulin and C peptide with diabetic retinopathy in Latinos with type 2 diabetes. BMJ Open Diabetes Res Care. 2014; 2:e000027.doi:10.1136/ bmjdrc-2014-000027.
Adams E, Genter P, Keefe E, Gray V, Rotter JI, Chen Y-DI, Ipp E. The GLP-1 Response to Glucose Does Not Mediate Beta and Alpha Cell Dysfunction in Hispanics with Abnormal Glucose Metabolism. Diab Res Clin Pract 2018; 135:185-191