Charles Grob, MD

Charles Grob, MD

Investigator, The Lundquist Institute
Professor of Psychiatry & Biobehavioral Sciences and Pediatrics, David Geffen School of Medicine at UCLA
Director, Division of Child and Adolescent Psychiatry, Harbor-UCLA Medical Center.

Contact

Email
cgrob@lundquist.org

Psychiatric research with hallucinogens

Research Description

Dr. Grob's clinical interests include mood and anxiety disorders, as well as the self-medication hypothesis of substance abuse as it applies to substance abuse. His research has included the first FDA approved Phase 1 study of the physiological and psychological effects of MDMA (3,4-methlyenedioxymethamphetamine), a multi-national, collaborative study of the Amazonian plant hallucinogen decoction, ayahuasca, in Brazil and a pilot investigation of the safety and efficacy of psilocybin in the treatment of anxiety in adult patients with advanced-stage cancer. His most recent research has examined the safety and efficacy of an MDMA treatment model with adult autistics with severe social anxiety.
Theme Groups
Neurotherapeutics
Research Interests
Clinical and Outcomes Research
Neurological Disorders

Education

  • BS, 1975, Columbia University, New York, NY
  • MD, 1979, State University of New York, Downstate Medical Center, Brooklyn, NY

Recent and/or Significant Publications

Grob, C.S, Danforth, A.L, Chopra, G.S, Hagerty, M.C, McKay, C.R, Halberstadt, A.L. and Greer, G.R. Pilot study of psilocybin treatment for anxiety in patients with advanced-stage cancer. Archives of General Psychiatry 68:71-78, 2011.
DOI
Grob, C.S, Bossis, A.P. and Griffiths, R.R. Use of the classic hallucinogen psilocybin for treatment of existential distress associated with cancer: in B. Carr and J. Steel (Eds.), Psychological Aspects of Cancer. New York, Springer, pp. 291-308, 2013.
DOI
Grob, C.S. The psychology of ayahuasca: in R. Metzner (Ed.), The Ayahuasca Experience: A Sourcebook on the Sacred Vine of Spirits. Rochester, Vermont, Park Street Press, pp. 63-93, 2014.
Amazon
Danforth, A.L, Struble, C.M, Yazar-Klosinski, B. and Grob, C.S. MDMA-assisted therapy: a new treatment model for social anxiety in autistic adults. Progress in Neuropsychopharmacology and Biological Psychiatry, 64:237-249, 2016.
DOI
Mithoefer, M.C, Grob, C.S. and Brewerton, T.D. Novel psychopharmacological therapies for psychiatric disorders: psilocybin and MDMA. Lancet Psychiatry 3:481-488, 2016.
DOI

Videos

Charles Grob MD Discusses Autism Social Anxiety on American Health Journal