Ronald Swerdloff, MD

Ronald Swerdloff, MD

Investigator, The Lundquist Institute
Chief, Division of Endocrinology, Harbor-UCLA Medical Center
Professor of Medicine, David Geffen School of Medicine at UCLA


Male Reproductive Medicine and Biology; Androgen Drug Development; Protective Effects of the Peptide Humanin

Research Description

Dr. Swerdloff’s research includes basic investigations, clinical trials, and translational studies. His research interests involve many aspects of basic male reproductive physiology and clinical reproductive investigation. Ongoing work includes the regulation of spermatogenesis, regulation of the androgen receptor gene, neuroregulation of gonadotropin secretion, development of male contraceptive agents, pharmacology of androgen hormones, regulation of spermatogenesis hormonal function in the testis, ethnic differences in the reproductive endocrine system, role of 5-alpha reduced androgens in the prevention and treatment of cognitive dysfunction, sexual dysfunction, impaired vitality, osteoporosis and frailty in elderly men, factors influencing male fertility, molecular basis and neurobiology of cognitive dysfunction in Klinefelter's Syndrome, sex steroid effects on cognition and neurodegenerative disorders, and mutant mouse models in reproductive biology, stem cell transplantation in the testes. Recent studies involve protection of normal tissue from the adverse effects of chemotherapy including onco-infertility, granulocytopenia, alopecia, brain dysfunction and cardiotoxicity.
Theme Groups


  • MD, 1962, University of California, San Francisco

Recent and/or Significant Publications

  1. Yue Jia, Jennifer Kuang Wei Yee2, Christina Wang3, Liana Nikolaenko4, Josh N. Cohen5, Samuel French6, Yan-He Lue3, Wai-Nang Paul Lee2 Ronald Swerdloff ; Testosterone and Non-Alcoholic Fatty Liver Disease--Friend or Foe, Endo2017 Florida April 2017
  2. YanHe Lue MD¹, Hemal Mehta MS², James Hoang BS¹, Kelvin,Yen PhD², Junxiang Wan PhD², Ronald Swerdloff MD¹, Pinchas, Cohen MD² and Christina Wang MD¹, ¹Division of Endocrinology, LABioMed at Harbor-UCLA; ²USC, Leonard Davis School of Gerontology, University of Southern, California, Los Angeles, CA(Presented By: YanHe Lue, MD); HUMANIN TRANSGENIC MICE ARE PROTECTED FROM YCLOPHOSPHAMIDE-INDUCED MALE GERM CELL APOPTOSIS; ASA American Society of Andrology Testis Workshop Florida April 2017
  3. Guillermo Galdon MD¹, Nima Pourhabibi Zarandi MD², YanHe Lue MD, PhD³, Ronald Swerdloff MD³, Stanley Kogan MD, FACS¹,4,5, Hooman Sadri-Ardekani MD, PhD¹,4,5 and Anthony Atala MD¹,4,5, Wake Forest Institute for Regenerative Medicine ; ²wake Forest Institute for Regenerative Medicine ; ³Division of Endocrinology, Department of Medicine, Harbor-UCLA Medical Center and Los Angeles Biomedical Research Institute; 4Department of Urology; 5Wake Forest School of Medicine (Presented By: Guillermo Galdon MD);
    IN VITRO CULTURE OF KLINEFELTER MOUSE SPERMATOGONIAL STEM CELLS, ASA American Society of Andrology Testis Workshop Florida April 2017
  4. Sherry Wu, Fiona Yuen, Ronald S. Swerdloff, Youngju Pak, Peter Y. Liu, William J. Bremner, Stephanie T. Page, Christina Wang : SINGLE, ESCALATING DOSE PHARMACOKINETICS, SAFETY, AND FOOD EFFECTS OF A NEW ORAL ANDROGEN 11β-METHYL-19-NORTESTOSTERONE 17β-DODECYLCARBONATE IN MAN: A POTENTIAL ORAL MALE HORMONAL CONTRACEPTIVE, Western Medical Regional Conference, September 25, 2017
  5. F. Yuen, S. Wu, R. Swerdloff, S. Page, P. Liu, C. Dart, D. Blithe, R. Sitruk-Ware, F. Bai, L. Hull, W. Bremner, B. Anawalt and C. Wang, Preventing Secondary Exposure to Women fromMen Applying A Novel Male Hormonal Contraceptive Gel. AFMR September 28, 2017


Ronald Swerdloff MD Discusses Chemotherapy Side Effects