Left to Right: Eiji Yoshihara, Jinhyuk Choi, Shudi Wang, Yu Hamba, Harvey Perez, Clarissa Tacto, and Fritz Cayabyab

Human pluripotent stem cell–derived islets hold great promise as a functional cure for diabetes. However, the absence of reliable markers to distinguish functionally competent islets has made their use in therapy somewhat of a gamble.