A team of researchers will use state-of-the-art brain imaging to unlock the secrets of a genetic disease, mucopolysaccharidosis (MPS), in a landmark study the team hopes will lead to new treatments for this devastating disease.
Employing a treatment framework in which clinicians administer different drugs in strategic succession could both treat bacterial infections and select against the development of resistance, Technical University of Denmark’s Lejla Imamovic and Morten Sommer argue today (September 25) in Science Translational Medicine. This new framework, which the researchers call collateral sensitivity cycling, could also help curb unnecessary antibiotic use, which is known to contribute to the emergence of drug-resistant superbugs.
While much of the obesity prevention efforts today focus on diet and exercise, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center (LA BioMed) researchers are going even further back in time to explore what happens during development in the womb that could lead to overeating and obesity later in life.
Michael G. Ross, MD, MPH, and Mina Desai, M.Sc., PhD, both LA BioMed lead investigators, recently received two grants to further their studies into influences on fetal development that can cause obesity.