Investigator(s): The Lundquist Institute

A team of researchers will use state-of-the-art brain imaging to unlock the secrets of a genetic disease, mucopolysaccharidosis (MPS), in a landmark study the team hopes will lead to new treatments for this devastating disease.

Investigator(s): The Lundquist Institute

The Scientist

By Tracy Vence | September 25, 2013

Employing a treatment framework in which clinicians administer different drugs in strategic succession could both treat bacterial infections and select against the development of resistance, Technical University of Denmark’s Lejla Imamovic and Morten Sommer argue today (September 25) in Science Translational Medicine. This new framework, which the researchers call collateral sensitivity cycling, could also help curb unnecessary antibiotic use, which is known to contribute to the emergence of drug-resistant superbugs.

While much of the obesity prevention efforts today focus on diet and exercise, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center (LA BioMed) researchers are going even further back in time to explore what happens during development in the womb that could lead to overeating and obesity later in life.

Michael G. Ross, MD, MPH, and Mina Desai, M.Sc., PhD, both LA BioMed lead investigators, recently received two grants to further their studies into influences on fetal development that can cause obesity.

Investigator(s): The Lundquist Institute

Paula R. Moore, the former executive director of the FRIENDS of Cabrillo Marine Aquarium, a nonprofit organization that supports the San Pedro-based aquarium, will be joining the Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center (LA BioMed) on Aug. 26 as the director of development.

Investigator(s): The Lundquist Institute

LOS ANGELES – (August 5, 2013) – With some 300 million people around the world living with asthma, a study by Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center (LA BioMed) researchers that was released ahead-of-print found for the first time that maternal smoking can cause the third generation of offspring to suffer from the chronic lung disease.

Investigator(s): The Lundquist Institute

LOS ANGELES – (August 1, 2013) –  The rise of antibiotic resistance among hospital-acquired infections is greater than the Centers for Disease Control and Prevention (CDC) found in its 2008 analysis, according to an ahead-of-print article in the journal,Antimicrobial Agents and Chemotherapy.

The article also finds that the Food and Drug Administration’s (FDA) promise to “reboot” antibiotic development rules a year ago to combat the rise in resistance has fallen short.

Investigator(s): The Lundquist Institute

For more than 60 years, the researchers at the Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center (LA BioMed) have been pioneering the medical advances that are saving lives and improving the health of people in the region and around the world.

Little, if any, of this would be possible without the support of the federal government through the National Institutes of Health (NIH).

Investigator(s): The Lundquist Institute

Hormone replacement therapy has plummeted among U.S. women since the Women’s Health Initiative cut short its Estrogen Plus Progestin Trial in 2002, when study results revealed that women who took the two-hormone therapy suffered adverse effects and higher mortality.

But the widespread rejection since of all hormone replacement therapies among menopausal women has been misguided, a team of researchers from the Yale School of Medicine in New Haven, Conn., wrote Thursday in the online edition of the American Journal of Public Health.

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Investigator(s): The Lundquist Institute

SAN FRANCISCO – (June 18, 2013) – Men who lose sleep during the work week may be able to lower their risk of developing Type 2 diabetes by getting more hours of sleep, according to Los Angeles Biomedical Research Institute (LA BioMed) research findings presented today at The Endocrine Society’s 95th Annual Meeting in San Francisco.

Investigator(s): The Lundquist Institute

Dr Matthew Budoff (Los Angeles Biomedical Research Institute, CA), a longtime researcher in the use of cardiac CT, described what he believes to be the most important uses for CT today [1].

First, CT angiography is emerging as “a single tool that gives us [information about] function and anatomy,” he told the audience.