This study is poised to generate crucial new Down Syndrome cell lines to study genetic defects specific to Down Syndrome.
Investigator(s):
Denise Al Alam, PhD
The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center (TLI) has announced that The California Institute for Regenerative Medicine (CIRM), one of the world’s largest institutions dedicated to regenerative medicine, has awarded $1.5 million to TLI Investigator Denise Al Alam, PhD, to support research that aims to understand lung disease in individuals with Trisomy 21 (also known as Down Syndrome). Although Trisomy 21 impacts multiple organ systems, respiratory complications are a significant cause of death in children and adults with this genetic condition.
Dr. Yoshihara will investigate cutting-edge transcriptional gene regulation processes.
Investigator(s):
Eiji Yoshihara, PhD
The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), a division of the National Institutes of Health, has granted Eiji Yoshihara, PhD, a principal investigator at The Lundquist Institute (TLI) and assistant professor at the David Geffen School of Medicine at UCLA, a five-year grant totaling $3 million. This prestigious NIH R01 grant, known for its rigorous peer-review process, is dedicated to advancing stem cell therapy research for treating diabetes.
The project will take a pioneering approach to unraveling sensory and autonomic neurons in the overproduction of IgE in allergic asthma
Investigator(s):
Nicholas Jendzjowsky, PhD
In a significant stride for respiratory medicine, Lundquist Institute (TLI) investigator Nicholas Jendzjowsky, PhD, has been awarded a prestigious grant from the National Institute of Health/National Institute of Allergy and Infectious Diseases (NIH/NIAID). This grant, totaling $298,800, not only underscores TLI's commitment to pioneering research and excellence in respiratory medicine and exercise physiology but also recognizes Dr. Jendzjowsky's expertise and the importance of his research.
The Lundquist Institute is proud to announce that Wei Yan, MD, PhD, a distinguished professor at the David Geffen School of Medicine at UCLA and Lundquist investigator, has been appointed by the American Society of Andrology and the European Academy of Andrology as the new Editor-in-Chief of Andrology, the highly-respected journal in the field of reproductive medicine.
Investigator(s):
Wei Yan, MD, PhD
Dr. Yan's appointment to Andrology is a testament to his dedication to reproductive medicine. With extensive editorial experience, including his previous roles as co-editor-in-chief of Biology of Reproduction and Senior Editor of eLife, he has significantly advanced the understanding of fertility and infertility since joining The Lundquist Institute in 2020 to direct the National Center for Male Reproductive Epigenomics.
Lundquist Investigator Loren Miller, MD, MPH, will be honored with a 2024 Top Ten Clinical Research Achievement Award by the Clinical Research Forum (CR Forum) at a Las Vegas, NV ceremony, on April 2, 2024. Dr. Miller is an Investigator at TLI, Chief of Infectious Diseases at Harbor-UCLA Medical Center, and a Professor of Medicine at the David Geffen School of Medicine at UCLA.
Investigator(s):
Loren Miller, MD, MPH
The Top 10 Clinical Research Achievement Awards honor groundbreaking achievements in clinical research nationwide. The award recognizes the Protect Trial, a clinical trial jointly led by Dr. Miller and senior investigator Susan Huang, MD, MPH, Chancellor’s Professor at the University of California, Irvine. The Protect Trial involved nearly 14,000 residents in 28 California nursing homes in Los Angeles and Orange counties.
This initiative seeks to improve emergency medical services in L.A. County by drastically reducing post-motor vehicle crash deaths through a new protocol mobile application
The California Office of Traffic Safety through the National Highway Traffic Safety Administration has awarded The Lundquist Institute, Los Angeles County Emergency Medical Services, and the Harbor-UCLA Department of Emergency Medicine a $1 Million grant to facilitate the development and implementation of an innovative mobile application aimed at enhancing prehospital trauma care.
Investigator(s):
Mohsen Saidinejad, MD, MBA, FAAP, FACEP
In the Pediatrics article, “The Management of Children and Youth Pediatric Mental and Behavioral Health Emergencies,” Dr. Saidinejad and his co-authors note that “mental and behavioral health (MBH) conditions affect as many as 1 in 5 children younger than 18 in the United States each year.” Given the increasing need for MBH treatment for children and youth, emergency departments in hospitals are now a critical access point and safety net as the wait time for child psychiatrists can be more than 40 days. Dr.
AHRQ-funded Study Finds “Universal Decolonization” Lowers Hospital Transfers Due to Infection from Methicillin-Resistant Staphylococcus aureus (MRSA)
Investigator(s):
Loren Miller, MD, MPH
Nursing homes that use a chlorhexidine bathing routine to clean the skin, and an over-the-counter antiseptic to clean the nose, prevent serious infections and reduce the amount of antibiotic-resistant organisms in the nursing home setting, according to the findings of researchers at Harbor-UCLA Medical Center, the University of California, Irvine, and the Centers for Disease Control and Prevention (CDC). The findings were published on October 10, 2023, in the New England Journal of Medicine.
The Lundquist Institute (TLI) Investigator, Harry Rossiter, PhD, has been awarded a five-year R01 grant totaling $3.8 Million from the National Institutes of Health’s National Heart Lung and Blood Institute (NIH/NHLBI). The R01 is the most prestigious and competitive NIH grant (only 10% are funded) awarded to biomedical researchers.
Investigator(s):
Harry Rossiter, PhD
Dr. Rossiter’s research team at TLI has developed the next generation of the cardiopulmonary exercise test; the standard clinical test to investigate exercise intolerance. The new test, termed muscle-CPET or “mCPET,” will for the first time, integrate direct assessments of neuromuscular performance, with the existing technology that assesses the function of the cardiovascular and pulmonary systems under the stress of exercise.
TRDRP Research grant and JDRF multi-PI grant will help to establish the basis of diabetes and provides new therapeutics
Investigator(s):
Eiji Yoshihara, PhD
Lundquist Institute investigator Eiji Yoshihara, Ph.D., has received two grants for the research related to type 1 and type 2 diabetes. A three-year $1.45 Million research award from The Tobacco-Related Disease Research Program (TRDRP) and a three-year total $300,000/institution, multi-institutional/multi-PI research grant from the JDRF (formerly known as Juvenile Diabetes Research Foundation). For the TRDRP research, Dr. Yoshihara’s lab and research collaborator Dr.